But the most common way to diagnose TB, visually checking sputum samples for the microbe that causes the disease, requires sophisticated equipment and trained personnel.

Only about 2.2 million TB cases annually are diagnosed and reported with sputum smear microscopy, the most widely available test.

Conclusion CT-guided core needle lung biopsy is a more sensitive diagnostic method to tuberculosis. Various study ways to biopsy preparation can improve positive rate.