Objective: To study the therapeutical effect of the decoction of Bu-Shen-An-Geng on peripheral menopause syndrome (PMS), and explore its action mechanism.

Climacteric syndrome was related to age, number of children, concerns of menopausal knowledge, general disease treatment and family function and other factors.

The methods of integral and the grade of syndrome elements can reflect the characteristics of TCM pathology and the rule of the syndrome in the sub-health state of perimenopausal syndrome.