One of the liver's function is to digest food, absorb nutrients and get rid of toxic substances.

Mice transplanted with HEALs exhibit humanized liver functions persistent for weeks, including synthesis of human proteins, human drug metabolism, drug–drug interaction, and drug-induced liver injury.

They found a significant decrease in a marker associated with cell damage, which can cause impaired brain, muscle, liver and kidney function as well as ageing effects on the skin.