Objective To compare local thrombolysis by catheter and systemic thrombolysis by venous in treatment of acute thromboembolic pulmonary hypertension.

The mechanism of pulmonary hypertension was reviewed. The clinical application of drugs, especially a few new compounds, for pulmonary hypertension was introduced.

Anticoagulants, which are an important part of therapy for many patients with idiopathic pulmonary hypertension, are controversial in ES, because of the high risk for bleeding complications.