Aberrant methylation may be the most common mechanism of inactivating cancer-related genes in lung cancer, and histone modification may be closely associated with DNA methylation.
2
本研究的目的是探讨GSTT1基因多态性与中国四川汉族人群肺癌遗传易感性的关系。
The objective of this study is to investigate the relationship between genetic polymorphism of GSTT1 and inherent susceptibility to lung cancer in Han population in Sichuan, China.
3
运用遗传流行病学的理论和方法,以肺癌病例的配偶做为对照,着重分析了肺癌家族史与宣威肺癌的关系。
Using method of genetic epidemiology, and selecting the spouses of lung cancer cases as control group, the relation between the family history of lung cancer patients and lung cancer was analysed.