Next to Batman, the 21st century's most recognizable Sherlock Holmes replicant is the irascibly brilliant Dr. Gregory House.

Whodunit: Next to Batman, the 21st century's most recognizable Sherlock Holmes replicant is the irascibly brilliant Dr. Gregory House (played by Hugh Laurie).

Only five children born in the U.S. annually have the same type of LCA as Morehouse, but focusing on a rare single-gene defect is a good way to develop a model for treating more common ailments.