铜绿假单胞菌耐药性

Resistance to Pseudomonas aeruginosa

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1
铜绿假单胞菌；标本分布；耐药率；药物耐药性监测。
Pseudomonas aeruginosa; distribution of samples; drug resistance rate ; drug resistance monitoring.
2
目的：检测铜绿假单胞菌耐药株PA36的耐药性R质粒与菌毛及粘附性的关系。
Objective To study the relationship between the resistance R plasmid and both pili and adherence of Pseudomonas aeruginosa strain, PA36.
3
结论铜绿假单胞菌的耐药性日趋严重，两类拓扑异构酶基因突变和泵出机制形成了铜绿假单胞菌对喹诺铜类药物耐药的主要机制。
The resistance to quinolones in clinical isolates of Pseudomonas aeruginosa is due to the mutations of two types of topoisomerase plus efflux pump.

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