Objective to study the differences of protein expression pattern between the Yin asthenia generating intrinsic heat patients with lupus erythematosus (SLE) and normal persons.

Objective: to evaluate the effect of Ziyin lupus capsule on systemic lupus erythematosus patients of Yin deficiency inner heat.

Most gene expressions, especially genes related to metabolism related, of excessive toxic heat and internal heat due to Yin deficiency of SLE have consistency.