食管癌遗传

Esophageal cancer heredity

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1
本研究旨在探讨XPC-PAT多态与食管癌遗传易感性的关系。
This study was therefore to assess the relationship between XPC-PAT polymorphism and susceptibility to esophageal squamous cell carcinoma (ESCC).
2
结果：食管癌先证者一级亲属的发病率(5。38%)明显高于对照一级亲属的发病率(2。81%)，食管癌遗传度为2 4。
Result: the results showed that incidence rate of the first degree relatives in cases was 5.38%, significantly higher than that in control cases (2.81%).
3
这一结果提示，食管癌患者、患者子女DNA损伤修复功能有缺陷，这种缺陷可能与遗传易感性有关。
The results demonstrated that the DNA repairing function in the patients with esophageal can-cer and their children had the defect, which may be related to the inherited susceptibility.

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