These findings suggest that aliskiren was as effective as an angiotensin receptor blocker in attenuating this measure of myocardial end-organ damage in hypertensive patients with LV hypertrophy.

Ang II infusion is a widely used experimental model of hypertension, because inhibitors of Ang II synthesis and action have been very effective clinically to treat hypertension.

Objective: To identify the association of M235T polymorphism of angiotensinogen (AGT) gene with essential hypertension complicated by brain infarction in Chinese Han population.