Methods: To collect 58 cases with NPC who have finished cervical lymph node biopsy and 60 cases just nasopharyngeal biopsy before treatment and diagnoses.

Conclusion: Using nasal endoscope in biopsy, the authors can examine repeatedly every point of nasopharynx to get deep tissue and the size of specimen, so that to diagnose nasopharyngeal carcinoma.

To evaluate the value of clinical application of CT-guided nasopharyngeal needle biopsy through mandibular notch.