Sirtris Pharmaceuticals, a firm based in Cambridge, Massachusetts, of which Dr Sinclair is a co-founder, has identified a number of synthetic molecules whose effecton yeast is many times more potent than resveratrol's.
"Pal Joey" is one of the all-time great Broadway musicals, a portrait of life on the bottom rungs of showbiz in which Richard Rodgers and Lorenz Hart teamed up to immensely potenteffect with John O'Hara ("Appointment in Samarra"), who wrote the book.