He has a comprehensive knowledge of medicine.

他有广泛的医学知识。

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Besides, a comprehensive knowledge of household management, social etiquette, education and domestic entertainment is needed.

此外，还应具备家务管理、社交礼仪、教育以及家庭娱乐等综合性知识。

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The paper makes a detailed comparison between several often used video file formats so that we can get a comprehensive knowledge of video files and use them better.

目前计算机中应用的视频文件格式很多，常常容易造成混淆而影响了它的正确使用。

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He exhibits a comprehensive knowledge of events, making very few factual slips.

ECONOMIST: American history

He wanted to make sure his workers kept up a comprehensive knowledge base, so when the Japanese offered to sell him integrated circuits at half price, he refused.

FORBES: Leadership

What might be a failing in terms of our comprehensive knowledge of the world, is a total win for marketers and app makers.

FORBES: If You Have A Great Idea (And $1,500) You Can Be A Google Glass Explorer