It is clear, moreover, that no one can profess indifference in a matter of such vital importance.

这是清楚的，况且，没有人可以自称冷漠，在短短的这种至关重要的。

youdao

Secretary Clinton said the U.S and Russia will continue to have disagreements, but added the treaty is an example of deep and substantive cooperation on a matter of vital importance.

VOA: standard.2010.03.26

This is a matter of vital importance for all of us and investment opportunities for many.

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