世界华人消化杂志 Key Words: LNAzyme; Hepatitis C virus; Hepatitis C; Antisense oligonucleotide; Gene therapy [gap=749]关键词: 锁核酸核酶; 丙型肝炎病毒; 丙型肝炎; 反义核酸; 基因治疗
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...中心 关键词 :NMDA受体;反义寡聚核苷酸;免疫组织化学;海马;大鼠 [gap=1020]Key words:NMDA receptor;antisense oligonucleotide;immunohistochemistry;hippocampus;rat ...
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VEGF antisense oligonucleotide VEGF反义核酸
antisense oligonucleotide ASODN 反义寡核苷酸
antisense oligonucleotide to NR2B 反义寡核苷酸
antisense oligonucleotide drug 反义药物
wt antisense oligonucleotide wt1反义寡核苷酸
p53 antisense oligonucleotide p53反义寡核苷酸
STAT3 antisense oligonucleotide STAT3反义寡核苷酸
antisense oligonucleotide probe 反义寡核苷酸探针
Conclusion: 1. Antisense oligonucleotide targeting survivin can downregulate the protein expression of survivin.
结果:1、Survivin 蛋白在 K562 细胞中呈高表达,转染反义寡核苷酸后 survivin 蛋白表达下调,而无义组及脂质体组无明显变化。
参考来源 - Survivin反义寡核苷酸联合足叶乙甙诱导K562细胞凋亡的实验研究The principle of this technology is the sequence-specific binding of an antisense oligonucleotide (ASOs) to target mRNA, thereby preventing gene translation.
其原理是反义核苷酸能与特定序列互补目标mRNA结合,从而阻止了目标基因表达。
参考来源 - 磁性纳米粒子—反义核苷酸复合物诱导HL·2,447,543篇论文数据，部分数据来源于NoteExpress
Phase II trials with an antisense oligonucleotide against HSP-27 in CRPC are underway.
以HSP-27为靶点的反义寡核甘酸正处于第二期临床试验中。
Objective: to screen the high performance, specific and nontoxic anti HBV antisense oligonucleotide fragment.
目的：筛选出高效特异而无毒的抗hbv反义寡核苷酸片段。
CONCLUSION: EAAC1 antisense oligonucleotide has the neuroprotective effect against acute cerebral ischemia injury.
结论：EAAC 1反义寡核苷酸对急性脑缺血损伤有神经保护作用。
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