With the thorough research of tumor mechanism, drugs acting on cell signal transduction pathway began to attract attention of researchers as an important target for anticancer drug development.
随着对肿瘤发生机制研究的深入，作用于细胞信号转导通路的药物开始引起研究者的关注，成为抗肿瘤药物研发的重要靶点之一。
In hyperosmotic stress, the HOG-MAPK pathway regulates the signal transduction and expression of numerous genes for cell survival.
该途径在高渗应激环境下控制信号转导和基因表达，是细胞生存所必需的。
Objective To evaluate the inhibiting effect of selective and non-selective cyclo-oxygenase-2(COX-2) inhibitor on growth of colon cancer cell lines in vitro and its signal transduction pathway.
目的探讨选择性及非选择性环氧合酶-2抑制剂（COX-2）对体外培养的结肠癌细胞生长的影响及其作用的信号传导通路。
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