...手性环境使对映异构体间呈现物理特征的差异而进行分离的，一般分为直接法和间接法，前者直接以手性流动相（chiral mobile phase，CMP）或手性固定相（chiral stationary phase，CSP）进行分离；后者是对映体混合物用...
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chiral mobile phase separation 手性流动相拆分法
Chiral Mobile Phase Additives 手性流动相添加剂
Chiral Mobile Phase Additive 手性流动相
a chiral mobile phase 手性流动相
chiral mobile phase addition 手性流动相添加剂法
using chiral mobile phase additives 手性流动相添加剂法
chiral mobile phase additives method 手性流动相添加剂法
Objective: to establish an HPLC method for the resolution of metoprolol enantiomer using chiral mobile phase additives.
目的：建立hplc手性流动相添加剂法拆分美托洛尔对映体的方法。
In part III to VI, ephedrine, tyrosine methyl ester, metoprolol, ibuprofen enantiomeric separation with chiral additive as mobile phase by high performance liquid chromatography are presented.
本论文的第三至第六部分介绍了高效液相色谱手性流动相添加剂法拆分麻黄碱、对羟基苯甘氨酸甲酯、美托洛尔、布洛芬对映体。
The effects of composition of mobile phase, the structure of solute and the column temperature on chiral separation were extensively studied. The chiral recognition mechanism was discussed.
考察了流动相组成、溶质结构和柱温对对映体分离的影响，并初步探讨了手性识别的机理。
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