Tobacco increased significantly the mutation rate of Salmonella typhia and the formation rate of CHO colony.

烟草能显著地提高伤寒沙门氏菌突变率和CHO细胞集落形成率；

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Results The cell viability, protein content, colony formation and DNA synthesis were significantly inhibited by MAPK ASO, the inhibitory rate was 52.6% , 50.5% , 54.9% and 47.5% respectively(P< 0.01).

结果：MAPK反义寡核苷酸可明显抑制细胞活力、蛋白质含量、集落形成和DNA合成，其抑制率分别为52。6%、50。5%、54。9%和47。5%，与对照组比较差异有显著性（P<0。01）。

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The survival rate was 195% by growth curve and 337.5% by colony formation.

生长曲线可见细胞增生活跃，增殖率195 %。

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