世界华人消化杂志 Key Words: Helicobacter pylori; Resistance; Efflux pumps; Inhibitors [gap=581]关键词: 幽门螺杆菌; 耐药; 外排泵; 抑制剂
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MDR efflux pumps 细菌多重耐药外排泵
Active efflux pumps 主动外排泵
Multi-efflux pumps 多药耐药泵
multidrug efflux pumps 排药剂出泵
antibiotic efflux pumps 抗生素排出泵
The overexpression of membrane proteins functioning as drug efflux pumps is one of the main mechanisms for multidrug resistance of Candida albicans.
膜转运蛋白高表达导致多药抗药是白念珠菌抗药性产生的最重要机制之一。
Mechanisms of antibiotics resistance includes: (1) target site modification; (2) production of inactive enzymes; (3) decrease of drugs penetrance; (4) expression of efflux pumps.
抗菌药物耐药机制包括:(1)靶位修饰;(2)产灭活酶;(3)药物渗透力下降;(4)外排泵表达。
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