A beautifully preserved boat, made around 3,000 years ago and discovered by chance in a muddy hole, has had a profound impact on archaeological research.

（考古学家）在一个泥泞的洞里偶然发现了一艘大约3000年前制造的保存完好的船只，其对考古学研究产生了深远的影响。

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Intertextuality theory has had a profound impact on the study of text.

互文性理论对文本研究具有深远的影响。

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Genetics has had a profound impact on cancer treatment in recent years.

遗传学近年来对癌症的治疗产生了深远的影响。

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Whatever controversy dogged the company with Mass Effect 3 and Dragon Age 2, Bioware has had a profound impact on the ascendance of Western RPGs.

FORBES: Bioware Co-Founders Ray Muzyka and Greg Zeschuk retiring

Video footage of previous hostages has had a profound impact on public opinion - most recently in the case of US journalist Daniel Pearl, who was killed in Pakistan, and also Nick Berg, killed in Iraq.

BBC: NEWS | Middle East | Evolving tactics of Islamic militants

The world rarely sees someone who has had such a profound impact on so many.

CNN: Jenni Rivera is mourned, but still inspires