Objective To observe the change of IP3 and IP3R-1′s expression in neurons of mice′s hippocampal CA1 and CA3,which had been treated by Apolipoprotein E gene knock-out(ApoE KO) and high-fat diet.
目的观察载脂蛋白E(ApoE)基因敲除(KO)及高脂饮食小鼠海马CA1和CA3区神经元内三磷酸肌醇(IP3)和三磷酸肌醇受体-Ⅰ(IP3R-1)表达的变化。
参考来源 - 载脂蛋白E基因敲除及高脂饮食小鼠海马CAGene knock-out and over expression are important tools to study genes’function,providing plenty of information for the maintenance of stem cell pluripotency.
基因敲除或导入是研究基因功能的主要手段,其为干细胞多能性维持的分子机制研究提供了大量信息。
参考来源 - Nanog基因转染表皮干细胞及对其生物学特性影响的研究·2,447,543篇论文数据，部分数据来源于NoteExpress
PHRASAL VERB To knock someone out means to cause them to become unconscious or to go to sleep. 使失去知觉; 使昏昏欲睡
The three drinks knocked him out.
这3杯酒让他昏昏欲睡。
PHRASAL VERB If a person or team is knocked out of a competition, they are defeated in a game, so that they take no more part in the competition. 淘汰
He got knocked out in the first inning.
他在第1局就被淘汰了。
→ see also knockout
PHRASAL VERB If something is knocked out by enemy action or bad weather, it is destroyed or stops functioning because of it. 破坏
Our bombers have knocked out the mobile launchers.
我们的轰炸机已经破坏了那些移动发射台。
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