现行的药物急性毒性研究技术指导原则(包括化学药和中药、天然药物)中明确:最大耐受量(Maximal tolerance dose, MTD):指动物能够耐受的而不引起动物死亡的最高剂量。
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The toxic test suggested that the maximal tolerance dose of mice with its extract a day was 220 times as much as clinical administration dose.
毒性试验表明,小鼠一天口服王老吉浸膏最大耐量为临床口服量的220倍。
To observe the acute toxicity and death of the mice to which calcium nanoparticles were given in maximal dose and obtain the lethal dose 50(LD50) or the maximal tolerance dose (MTD).
观察小鼠一日内给予大剂量钙纳米粒子的急性中毒及死亡情况,得出半数致死量(LD50)或最大耐受量(MTD)。
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