Methods Immunohistochemical method was applied to observe the expression of NF-kB in the villus of patients with early spontaneous abortion.

方法通过免疫组织化学方法检测早期流产患者绒毛组织中的NF-kB的表达情况。

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Upon ligand engagement, these receptors in turn engage MyD88 which signals through IRAK4 to turn on a variety of pathways, including NF-kB and the secretion of pro-inflammatory cytokines.

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Through further experiments in human cells and animal studies the researchers found that a protein called NF-kB lured zinc into the immune cells that responded fastest to fight infection.

BBC: Zinc 'keeps immune system in check'

Once inside, the zinc then put the brakes on further activity in the NF-kB pathway, slowing down the immune response and limiting the amount of inflammation, the study, in Cell Reports, indicated.

BBC: Zinc 'keeps immune system in check'