AIM: To investigate the effects of MK-447 on platelet shape change, aggregation, and ATP release by collagen (col), ADP, and stable analogue of thromboxane A2 (STA2) in rabbits.

目的：研究MK - 447对胶原、ADP及血栓素a_2稳定类似物(STA_2)诱导的血小板变形、聚集和释放反应的影响。

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This may be effective in reassembly of the cytoskeleton, change of platelet shape and secretion during activation of the platelet.

这一作用可能在血小板活化时细胞骨架重组、形态改变和分泌内含物等一系列变化中起重要作用。

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