abstract:A prelingual deaf individual is someone who was born with a hearing loss or someone whose hearing loss occurred before they began to speak. Infants usually start saying their first words around one year, therefore for a child to be considered prelingually deaf, they would have to have lost their hearing before age one (which is the age at which the majority of hearing losses in children occur).
Conclusion the mutations in GJB2arethemajorcauseofprelingual deafness; twocausativemutations can be found in (28.6%) prelingualrecessiveand in (18.9%) prelingual sporadic NSHL patients.