"It helps us back out of the mind set that said something that doesn't work as a single agent isn't going to be a good drug, " said Dr. Winer.

WSJ: Breast-Cancer Drugs Raise Hopes

Exercisers that set goals with Preva are proven to work out on average one day more per week than those that don't.

ENGADGET: Preva Mobile for iOS aims to track your workouts, keep you going to the gym

The two young women hopped on a train and headed over there, and set to work creating what Saniewska says became Lady Gaga's first photo shoot, although Saniewska didn't know that at the time.

CNN: Before she was Gaga: The unseen photos