Objective1. To observe the effect of cortical spreading depression(CSD) on firing rate of trigeminal nucleus caudalis(TNC) neurons in rats so as to determine the correlation between CSD and central trigeminovascular neurons.2.
目的1.观察大鼠皮层扩布性抑制(CSD)前、中、后三叉神经脊束核尾侧亚核(TNC)神经元放电频率的变化,以及盐酸氟桂利嗪对其的影响,以了解CSD与三叉神经血管反射中枢之间的联系。
参考来源 - 偏头痛与丛集性头痛的疼痛发生机制研究·2,447,543篇论文数据，部分数据来源于NoteExpress
Objective to examine whether spreading depression (SD) precondition can induce brain ischemic tolerance.
目的验证扩散性抑制(SD)可诱导脑缺血耐受。
Studies in recent years have found that cortical spreading depression (CSD) may be one of the important mechanisms for the cause of migraine.
近年来的研究发现，皮质扩散抑制(CSD)可能是偏头痛发病的重要机制之一。
Its pathogenesis is still not completely clarified, animal models are established on the basis of trigeminovascular theory, cortical spreading depression theory and neurovascular theory.
其发病机制至今尚未完全明了，动物模型基于三叉神经血管学说、皮层扩散抑制学说和血管学说等理论而建立。
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