Those men who never smoked fared even worse, with a two-fold increase in risk.

那些从不吸烟的男性进展更糟糕，风险增加两倍。

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When the surgeon general issued a “call to action” on childhood obesity in 2001, about 13 percent of children were obese, a more than two-fold increase from the previous 20 years.

到2001年卫生局长呼吁对儿童痴肥问题采取行动时，13%的儿童痴肥，这比二十年前翻了两倍。

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With policing severely curtailed, counterfeiting took off in 1995—Qian estimates a nearly 100-fold increase in the production of fakes within just two years.

由于监管力度削弱了，1995年造假行为开始泛滥。 据易千估计，仅在两年内仿冒品生产数量就增加了100倍。

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Gestational diabetes - which affects four in 100 pregnancies - was associated with a two-fold increase in the risk of autism, while bleeding in pregnancy was alleged to carry an 81% increased risk.

BBC: Problem pregnancy 'autism risk'

Based on strong fiscal third quarter results reported in late April, management expects a two-fold EPS increase by 2015.

FORBES: Brinker International's Rise in Revenues

New drilling technologies have led in recent years to a modest increase in U.S. oil production, and over the past two decades, to a six-fold increase in U.S. conventional natural gas production.

FORBES: Angry Over Oil Price? Demand A Change In Fed Policy