You must give it to grandfather and he'll tell you what to do with it.

你必须把它交给爷爷，他会告诉你怎么处理的。

youdao

He didn't know what to do with it, so he sought advice for his teacher.

他不知道该做什么，所以他向他的老师寻求意见。

youdao

It was not the first motherless lamb he had found and he knew what to do with it.

这不是他第一次发现失去母亲的羊羔，他知道该怎么处理它。

youdao

It is a way to get scientists to talk with the general public about what they do.

VOA: special.2010.05.14

We've had a great deal to do with it, but of course we still haven't the slightest idea what it is.

我们花了很大的功夫来接解决这个问题，但我们仍然一点都不知道语言是什么。

耶鲁公开课 - 文学理论导论课程节选

The exception is right there. It's an index error, that is it's trying to do something going beyond the range of what this thing could deal with.

但他事实上抛出一个异常，异常就在这里，这是一个下标错误,它是试图去取超出范围的元素造成的。

麻省理工公开课 - 计算机科学及编程导论课程节选

Miss Masterman said she would decide what to do with it once she saw it.

BBC: Pink Floyd house sold at auction for ?1.2m

"There's too much money and people don't know what to do with it, " she says.

BBC: Canada boomtown under pressure

The crowd had so much excited energy and no idea what to do with it.

FORBES: What you say and do on social networks can be used against you in a court of law