Monotherapies are therefore the primary force behind the spread of artemisinin resistance.

因此，单方疗法是造成对青蒿素耐药性扩散的主要因素。

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The likelihood of drug resistance is increased with the use of single-drug therapies for malaria, especially monotherapies of artemisinin and its derivatives.

使用单一药物尤其是青蒿素及其衍生物的单一药物治疗疟疾可能会增加耐药性。

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