... but without success 但未能成功 without a single success 一事无成 Mostly Without Success 但大多不成功 ...
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Life is not the game of life, or it will be without a single success; can't live without game, otherwise monotonous boring.
生活不能游戏人生，否则就会一事无成；生活不能没有游戏，否则就会单调无聊。
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For example, the investment required to bring a single new medicine to market far exceeds a billion dollars without any certainty of success.
FORBES: Merck CEO: Health Care Beyond the Fiscal Cliff Requires Structural Changes
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