The most significant change is that new ITINs will now expire after five years .
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Movie theaters saw no statistically significant change in ratings enforcement at the movie box office.
But it's a significant change to the convention that block grants come without strings attached.
This may not sound like a significant change but things do look noticeably different.
"This is a significant change and not necessarily tied to business cycles, " says Mr. Headd.
Yet, if we look at this significant change through a different lens, another picture emerges.
But the most significant change was the shift in the balance of power across the Atlantic.
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In making this pretty significant change, the setup provided by Y Combinator has been fantastic.
Interestingly Samsung sees significant change in the shape of the smartphone market this year.
Bilsborough says the most recent significant change was in 2007 when the company removed artificial colourant from its chocolates.
In contrast, the standard-treatment group showed no significant change from baseline on any of the above measures.
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That's a pretty significant change, as the previous policy boasted data retention limits of only 90 days.
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When Ben Bernanke became chairman of the Federal Reserve in 2006 he promised a significant change.
Levels of violent crime estimated by the Crime Survey showed no statistically significant change in the year.
The data shows that there is no significant change in business from one week to the next.
That is a big and significant change, given his history of deep suspicion and hostility to armed republicanism.
Usually, companies that undergo a significant change in ownership risk having major restrictions put on their tax benefits.
Through their leadership and commitment we now have the first significant change in school meals in thirty years.
WHITEHOUSE: Bringing Healthy, Affordable Food to Underserved Communities | The White House
Nine percent of white children lived with at least one grandparent, "a significant change, " the census report said.
Under new leadership and with significant change, we have made notable improvements in infection control since Ms Gibb's departure.
Those words were welcomed as a "significant change in tone" by John Edmonds, general secretary of the GMB union.
"We've seen a significant change in a short period of time, " says H.
"The revision for which the claimants contend would be a very significant change from his written evidence, " she said.
If that plan passed, it would be a significant change from the offers that Republicans and Democrats last floated.
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Perhaps the most significant change of direction in the American debate comes from the result of last November's presidential election.
The report concluded that since 2008, "there has been no significant change in the proportion of adults meeting the recommendations".
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Wal-Mart serves more than 100 million U.S. customers every week and a significant change in this figure is highly unlikely.
This is "the most significant change we've made to our platform since we launched it four years ago, " Taylor said.
CNN: Facebook revamps site with 'Timeline' and real-time apps
Next up is the most significant change with Windows Phone 7.8, and Redmond's sole kudo: the ability to re-size Live Tiles.
ENGADGET: Windows Phone 7.8 hands-on: cosmetically yours Hands-on
The most significant change of the last 10 years is the emergence of consumers as the most powerful force in marketing.
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