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They would naturally hybridize and form a duplex, or a double stranded nucleic acid.
它们会自然杂交并形成双螺旋,或者说双链核酸
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When it cuts it leaves sticky ends or un-base paired single stranded regions on each end of the part its cut and that's just a property of many restriction enzymes; not all, some cut blunt,just right down the middle.
它切割后会留下两个粘性末端,或者未配对的单链部分,这是许多限制性内切酶的特性,但不是全部,有些限制性内切酶是从中间钝切的
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Certain double stranded RNA sequences will cause in the cell a process of degradation of very specific RNA sequence.
一些双链RNA序列能够在细胞中开启,特定RNA序列的降解程序
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You put this chromosomal DNA or this DNA that you're interested in, double stranded into a test tube.
你把这个染色体DNA,或者你感兴趣的双链的DNA,放进一个试管
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Transcription just means making a single stranded RNA copy of a sequence of base pairs in a DNA.
转录的过程就是从一段DNA碱基序列中,复制出一段单链RNA
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When it sees that sequence in a double stranded DNA it will bind there and it will cut.
当它在双链DNA中发现这个序列,就会与之结合并切割
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This is - what this diagram shows you is-- the forces that hold these individual strands of DNA into a double stranded form.
你们可以看看这个图表,演示了连接两条DNA长链为双螺旋,结构的化学力
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The end result of transcription is not double stranded DNA, it's single stranded RNA where the RNA that's produced is called messenger RNA.
最终的转录产物并非双链的DNA,而是单链的RNA,称为信使RNA
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It doesn't cut straight across the double stranded DNA but it cuts in this jagged fashion.
它不直接横切双链DNA,而是留下一个锯齿形切口
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The DNA molecule here has been spread apart, opening up two single stranded DNA's which have complementary base sequences because they were double stranded DNA.
这里DNA分子被分开,形成两条单链DNA,这两条单链碱基序列互补,因为它们是由双链DNA解旋形成的
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I'm going to start by talking about a very specific and interesting form of double stranded DNA called a plasmid and plasmids occur in nature.
我要从一种十分特殊,并有趣的双链DNA开始,这种双链DNA被称为质粒,它在自然界就存在
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It exists in a double stranded form where every strand is matched by its complement.
这种碱基配对存在于DNA双链中,每条单链都与其互补链,通过这个原则配对组合
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A new single stranded DNA is formed on each one of these open single strands.
对两条打开的单链进行复制,会生成两条新的DNA单链
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The result of this process if this replication went down the whole length of the DNA would be to form two identical, double stranded DNA molecules.
如果复制过程在整条链上持续进行的话,将生成两条完全一样的,双链DNA分子
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It's a double stranded circular piece of DNA, meaning that the 3', 5'ends that hang off are joined back together again to form a continuous loop.
它是双链环状DNA,它的3'末端和5'末端首尾相连,构成一种连续环状结构
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If I took two double stranded DNA molecules and I exposed them to certain conditions that caused them to denature, that means its native structure falls apart.
假如我把两条DNA双链,放在特定的条件下,使它们变性,变性表示使它们的原始结构分开
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Now, in your book, there's an example of plasmid where I've given you the exact sequence of nucleotides that makes up the whole double stranded DNA molecule.
现在在你们书里,有个质粒样本,我将组成这个双链DNA分子的,核苷酸序列写在这里了
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That only strands that have this exact complement can form double stranded DNA.
这表示只有两条链的碱基对,完全互补才能形成DNA双链
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It's very important in the biological operation of human cells and that step is RNA splicing, or processing of this RNA, single stranded RNA that's produced by transcription.
而这对人类细胞生物运作至关重要,这个步骤就是RNA剪接,或者说是对RNA的加工,对转录出的单链RNA进行加工的步骤
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It has to do with the nature of this complementary binding between double stranded DNA and the fidelity of this base pair matching in forming stable DNA molecules.
这些特性能从根本上解释,为何DNA双链的碱基能互补配对,以及在形成稳定的DNA分子结构时,碱基互补配对为何具有一致性
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It turns out to activate RNA interference, you deliver double stranded RNA.
要激活RNA干扰效应的话,可以将双链RNA转进细胞
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The end result is you can design now very specific double stranded RNA sequences, that when delivered into cells again will activate this process of natural degradation of an existing messenger RNA.
最终的结果是,你现在能够设计针对性很强的,双链RNA序列,当这段序列被转入细胞后会激活,对已有信使RNA进行降解的过程
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