Objective To investigate the effect of bradykinin (BK) on tight junction (TJ) of the blood-tumor barrier (BTB) and interendothelial TJ of capillaries in brain glioma rats.
目的研究缓激肽(BK)对脑胶质瘤大鼠血肿瘤屏障紧密连接的影响。
Once disseminate tumor cells pass through the blood-brain barrier, the brain microenvironment could elicit both inhibiting and promoting effects on tumor colonization and outgrowth.
一旦转移的肿瘤细胞穿过血脑屏障,脑微环境会对肿瘤定植和生长同时发挥抑制和促进作用。
Since most of the chemotherapy drugs cannot pass the blood-brain barrier, the effect of chemotherapy for brain tumor is disappointing.
由于大部分化疗药物难以通过血脑屏障,脑部肿瘤的化疗效果不佳。
Radiation therapy for tumors is that radioactive substances is directly placed in the tumor residual cavity, to avoid the blood-brain barrier and improve local drug concentration.
瘤内放射治疗是将放射性药物直接置于肿瘤残腔内,直接作用于胶质瘤细胞,此法能避开血脑屏障同时也能提高局部药物浓度。
Radiation therapy for tumors is that radioactive substances is directly placed in the tumor residual cavity, to avoid the blood-brain barrier and improve local drug concentration.
瘤内放射治疗是将放射性药物直接置于肿瘤残腔内,直接作用于胶质瘤细胞,此法能避开血脑屏障同时也能提高局部药物浓度。
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