Northern Ireland are fifth in Group Three after picking up just one point from their opening three qualifiers.
Leicester and the Blues both made winning starts in Group B, despite being handed tricky assignments.
The four teams in Group A are very close, so any result can help.
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Republic of Ireland were drawn in Group Eight along with world champions Italy and Bulgaria.
South Korea are top seeds in Group 3 which also includes Jordan and Turkmenistan.
Russia finished second behind Spain on six points in Group D, three ahead of Sweden.
Ivory Coast are in drawn in Group G with Brazil, Portugal and North Korea.
Mali will play in Group B of the competition alongside Kenya, Senegal and Burkina Faso.
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As well as Brazil the Flying Eagles will play Switzerland and South Korea in Group F.
Last season's finalists Manchester United take on CSKA Moscow, Besiktas and Wolfsburg in Group B.
Big-spending Real Madrid have been drawn in Group C, along with AC Milan, Marseille and Zurich.
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The Flying Eagles have been beaten by both Spain and Venezuela in Group B of the competition.
Arsenal chief executive Ivan Gazidis was also wary about the opposition his side face in Group H.
Senegal are in Group D in the Africa Cup of Nations along with Tunisia, Angola and South Africa.
The SPL champions have one point from two matches in Group E - three behind United and Villarreal.
The two were forced to go to the one-off play-off in Khartoum after finishing level in Group C.
The 16-team tournament, played every four years, sees defending champions Iraq facing Iran in Group D on Tuesday.
Three-times world champions Germany are drawn with Cameroon, Ireland and Saudi Arabia in group E for the finals.
Slovenia have been drawn in Group B of the World Cup finals alongside Paraguay, South Africa and Spain.
In Group I of the Europa League, Jorge Jesus' encarnados join Everton at the top with six points.
Victory over San Marino could see Northern Ireland leap into second place in Group Three on goal difference.
Arsenal were drawn in Group H alongside Dutch side AZ Alkmaar, Greek side Olympiakos and Belgium's Standard Liege.
Meanwhile in Group D Burkina Faso 's match against New Zealand took much longer than expected to complete.
The Ibrox outfit have been drawn to face Sevilla, Stuttgart and Romanian champions Unirea Urziceni in Group G.
Liberia have been drawn in Group Six of the World Cup qualifiers to play Senegal, Gambia and Algeria.
The Black Stars have been unimpressive despite winning their opening two games in Group A of the tournament.
Chelsea now sit one point behind Roma in Group A, who leapfrogged them with a win over Cluj.
The defeat leaves N Ireland with just one point from their three qualifiers and lying fifth in Group Three.
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