Then there is the ticklish issue of multinationals testing drugs in a poor country.
The devil within the details of something as ground-breaking as this will be ticklish indeed to sort.
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To make matters more ticklish, there was a half-mile of unplowed driveway between us and the main road.
Depending on what he says, it could be a ticklish situation for Thomson Reuters and Fortune magazine.
On two of Turkey's most ticklish issues, the Kurds and Cyprus, he has yet to give much ground.
Before that happens, America must square up to some of those ticklish legal and moral questions that drones raise.
Military reform will require politically ticklish choices about which installations to shut down.
But in the meantime, Petke faces a ticklish dilemma as he tries to plug the holes in his team's leaky defense.
He has a startling record of assembling hair-thin majorities for ticklish pieces of legislation, such as on Medicare prescription-drug benefit in 2003.
For Tony Blair, empire is a ticklish subject nonetheless and not just because his ministers keep being reminded of it when they venture abroad.
The other most ticklish issue was whether the presidential election, which most independent observers reckoned was rigged, would be run again and, if so, when.
These are the sort of ticklish questions that the 8, 500 partners of the two firms must now ponder before deciding whether to approve the deal.
The joy that Charlie and Yvonne take in doing good has the erotic quality of a shared secret, a ticklish pleasure that only they know about.
If true, the question of why Vajpayee entrusted such an important ministry to Fernandes will be just one of the many ticklish issues the PM must confront in the months ahead.
All this sets a ticklish task for Mr Obama.
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It's more ticklish when chang's on offer, since it's (a) funky tasting, (b) knee wobbling when consumed in quantity, and (c) very possibly homemade, so that not quaffing it down may bruise feelings.
In particular, there is the ticklish issue of how much to disburse on preventing and treating now, and how much to reserve for research into better ways of doing things in the future.
But at the very least it is likely to raise the prices of electricity, natural gas and petrol, as energy firms pass on the expense of buying permits to their customers a ticklish prospect at a time when voters are already enraged by rising energy prices.
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