Arthritis and rheumatism are prominent crippling diseases.
关节炎和风湿病是常见致残的疾病。
The high cost of capital has a crippling effect on many small firms.
高资本成本对许多小公司有着极坏的影响。
Arthritis is a crippling disease which affects people all over the world.
关节炎是一种严重影响健康、困扰全人类的疾病。
I wouldn't go back to the crippling self-consciousness of my youth if you paid me.
就算你给我钱，我也不会回到年轻时那种自我意识严重的状态。
Performance anxiety can be crippling.
表现性焦虑可能会带来严重后果。
Students graduate with crippling debts.
学生们背负着沉重的债务毕业。
Endless loans left the continent with crippling debt.
没完没了的借贷把沉重的债务留给非洲大陆。
It's also expected to ease some of Nairobi's crippling traffic.
他同时也希望通过这条道路缓解内罗毕糟糕的交通状况。
Parts of the country are continuing to suffer from a crippling drought.
我国的部分地区正持续遭受严重的干旱。
For coastal communities, the impact of these two blows could be crippling.
对于海岸居民而言，两次连续的打击将是难以承受的。
Without trees, Haiti lost its topsoil through erosion, crippling agriculture.
没有了树木，海地土壤流失，重创了当地农业。
If that happens, the burden of repaying the foreign debt then becomes crippling.
如果出现这种情况，偿还外债的负担则会变得极其严重。
To stay afloat, they need to drive down costs without crippling their core business.
为了摆脱困境，音乐公司需要在不损害其核心业务的前提下压缩成本。
Tutankhamun's bone disease was crippling, but on its own would not have been fatal.
图坦卡蒙的骨病固然严重，但还没到让他送命的地步。
It is a crippling population problem that could be worse than any global economic slowdown.
人口年龄层失衡的问题，将比全球经济衰退更严重。
In a winter marked by several crippling storms, the storm of February 1-2, 2011, stands out.
在冬季的几场十分严重的暴风雪中，2月1 - 2号的暴风雪格外突出。
In Australia, falling wool prices in the 1990s and crippling droughts hit the industry hard.
在澳大利亚，90年代羊毛价格的持续下降和严重的旱灾极大地冲击了这个产业。
As a result, many suffer conditions ranging from mild dental fluorosis to crippling skeletal fluorosis.
其结果是，许多人患有各种不同病症，轻则牙氟中毒，严重者致残性氟骨症。
Krait and cobra venoms, including that of the king cobra, act very quickly by crippling the nervous system.
金环蛇和眼镜蛇(包括眼镜王蛇)的毒液，通过削弱神经系统快速生效。
Mills are expensive to turn off and on, while the capital needed to open up a new mine site is crippling.
钢铁厂开开停停很费钱，而开采一个新矿场需要大笔资金。
In severe cases, it can cause changes to bone structure, calcification of ligaments, and crippling effects.
情况严重者，还可能导致骨骼结构变化，韧带钙化以及致残等后果。
Another crippling characteristic of thin clients is that nearly all user interaction is at the page level.
瘦用户机的另一个缺陷就是几乎所有的用户交互都发生在页面级别。
That limitation is crippling because many of the most common design patterns rely on being able to pass this as an argument.
这一限制的影响极大，因为许多最常见的设计模式都要依赖于能够将this作为参数传递。
That may be understandable: panic was in the air, AIG faced crippling collateral calls and Lehman Brothers had just folded.
这是可以理解的：当时一片恐慌，AIG面临着严峻抵押赎回压力且雷曼兄弟刚刚破产。
But I also know that sanctions without outreach — condemnation without discussion — can carry forward only a crippling status quo.
我也知道，如果一味制裁而没有主动接触，如果一味谴责而没有对话，只能保持一个有害的现状。
And so it's not, perhaps, crippling if this is the conclusion we reach, but at the same time it's not the only possible conclusion.
因此，如果这就是我们的结论，也没有太大关系，但同时要知道这不是惟一可能的结论。
And so it's not, perhaps, crippling if this is the conclusion we reach, but at the same time it's not the only possible conclusion.
因此，如果这就是我们的结论，也没有太大关系，但同时要知道这不是惟一可能的结论。
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