Her father carried a heavy burden of responsibility.
她父亲肩负着重大责任。
On occasion, that can prove a heavy burden indeed.
有时，这的确可能成为非常沉重的负担。
Poverty on an old man's back is a heavy burden.
老而贫困，负担最沉。
That's a potentially heavy burden if he doesn't feel like doing much.
如果他不想做太多，这无疑是个沉重的负担。
He shouldered the heavy burden of leadership.
他肩负着领导的重担。
So I don't have a heavy burden in mind and can stay happy.
所以我并没有太大的压力，并且始终可以很快乐！
When thousands of people are depending on you, that is a heavy burden.
当数千个人都依靠你的时候，这就成了一项繁重的负担。
We went over hills and rivers with the heavy burden on the shoulders.
我们扛着那沉重的柴禾翻山过河。
By the loss of this friendship I found myself relieved from a heavy burden.
失去了他的友谊，我倒是卸下了一个沉重包袱。
That is a heavy burden for a country where tax revenues amount to just 15% of GDP.
这对于一个税收只占GDP15 %的国家来说是很重的负担。
While these cases were relatively rare, they imposed a heavy burden on intensive care units.
虽然此类病例相对少见，但对重症监护科室造成了沉重负担。
In most poor countries, excessive business regulations place a heavy burden on entrepreneurs.
在最贫穷的国家，烦琐的商业规则给创业者带来了沉重的负担。
Jiang says the amount of vegetable waste in the county has become a heavy burden on local agriculture.
蒋海宏表示，镇上蔬菜废弃物的数量已经成为当地农业的一个重负。
She told me that even at a young age William found the prospect of being king a really heavy burden.
她告诉我，自小，威廉就意识到将来成为国王需要承担很大的压力。
Bill Lacey of the South African Chamber of Business worries that this places a heavy burden on small firms.
南非商会的比尔担心这会给那些小公司带来很重的负担。
Having the DBMS determine the optimal access path to the data lifts a heavy burden off the programmer's shoulders.
让DBMS确定到数据的最优存取路径解除了程序员肩上沉重的负担。
If we know that we did the right thing, even if the outcome wasn't ideal, it can help lighten the heavy burden of remorse.
如果我们肯定自己做了正确的事情，即使结果并不理想，客观判断力依然会帮助减轻自责的重担。
However, history shows us that while great knowledge can sometimes be a heavy burden, it always has outweighing benefits.
然而，历史表明，尽管伟大的知识有时会成为一种沉重的负担，但它总会带来更多的福祉。
I devoted myself to study and to explore by wisdom all that is done under heaven. What a heavy burden God has laid on men!
我专心用智慧寻求查究天下所做的一切事，乃知神叫世人所经练的是极重的劳苦。
They cause immense suffering, place a heavy burden on health care services, and carry enormous consequences for societies and economies.
这两种疾病会给人带来极大的痛苦，使卫生保健服务背上深重的负担，并且会造成巨大的社会和经济后果。
On this Memorial day, and every day, we bear a heavy burden of responsibility to uphold the founding principles so many died defending.
在阵亡将士纪念日这一天，在每一天，我们重任在肩，必须维护众前辈以生命捍卫的建国原则。
A coward considers difficulties as a heavy burden on his back, but a valiant fighter turns difficulties into a steppingstone for his advance.
懦夫视困难为压在其后背的一项重负，而勇者把困难转化为其进步的台阶。
A coward considers difficulties as a heavy burden on his back, but a valiant fighter turns difficulties into a steppingstone for his advance.
懦夫把困难当做沉重的包袱，勇士把困难化作前进的阶梯。
Without the heavy burden of tradition and history, the Directors of the Fifth Generation in China have sought a completely new aesthetic space.
我国“第五代导演”由于没有传统和历史两大包袱的重负，寻找到了一种新的审美空间。
It is time for countries with rapidly growing economies and a heavy burden of multidrug-resistant tuberculosis to step up their commitment and financing.
对那些经济增长很快并且面临耐多药结核病沉重负担的国家而言，现在到了加强承诺并提供资助的时候了。
It is time for countries with rapidly growing economies and a heavy burden of MDR-TB to step up their commitment and financing for their own MDR-TB programmes.
对那些经济增长很快并且面临耐多药结核病沉重负担的国家而言，现在到了加强承诺并为自身的耐多药结核病项目提供资助的时候了。
It is time for countries with rapidly growing economies and a heavy burden of MDR-TB to step up their commitment and financing for their own MDR-TB programmes.
对那些经济增长很快并且面临耐多药结核病沉重负担的国家而言，现在到了加强承诺并为自身的耐多药结核病项目提供资助的时候了。
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